Psychiatric Genomics Consortium Autism GWAS Summary Statistics

PGC Autism Spectrum Disorder GWAS summary statistics contain genome-wide association study results for Autism Spectrum Disorder phenotypes from the Psychiatric Genomics Consortium. The dataset is structured as multiple publication-specific subsets, each loadable independently via the Hugging Face Datasets library. It was published by OpenMed and last updated on April 6, 2026.

Use Cases

• Meta-analyze SNP effect sizes and p-values across different PGC Autism GWAS publications.
• Identify significant genetic loci by comparing p-values and odds ratios across different summary statistics subsets.
• Calculate polygenic risk scores by integrating effect size estimates (beta) and allele frequency data.
• Replicate genetic association findings by comparing summary statistics from the 'asd2017' subset with newer studies.
• Assess linkage disequilibrium patterns using provided SNP identifiers and chromosomal positions.

Strengths

• Data originates from the authoritative Psychiatric Genomics Consortium (PGC).
• Provides multiple GWAS publications as separate, independently loadable subsets.

Limitations

• Specific sample sizes, number of SNPs, and column definitions for each subset are not provided in the input.
• The temporal coverage and geographic origin of the underlying participant cohorts are unknown.

Provenance

Source

Psychiatric Genomics Consortium (PGC).

Collection Method

Genome-wide association study (GWAS) summary statistics.

Freshness

Last updated on April 6, 2026.