PGC Major Depressive Disorder GWAS Summary Statistics

Genome-wide association study summary statistics for Major Depressive Disorder phenotypes from the Psychiatric Genomics Consortium. The dataset is organized by publication, with each available as a separate subset. It was uploaded by OpenMed and last updated in April 2026.

Use Cases

• Identify genetic variants associated with Major Depressive Disorder using p-values and effect sizes from summary statistics.
• Perform fine-mapping of risk loci by analyzing linkage disequilibrium patterns with SNP identifiers and chromosomal positions.
• Calculate polygenic risk scores by aggregating SNP effect sizes across the genome.
• Conduct cross-trait genetic correlation analyses using Z-scores and standard errors from different GWAS subsets.

Strengths

• Data originates from the authoritative Psychiatric Genomics Consortium.
• Structured by publication, allowing focused analysis on specific GWAS results.

Limitations

• Specific sample sizes, variant counts, and statistical power for each study are not provided in the description.
• The dataset may lack individual-level data, limiting analyses to summary-level statistics.

Provenance

Source

Psychiatric Genomics Consortium (PGC)

Collection Method

Genome-wide association study meta-analysis.

Time Range

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Freshness

Last updated in April 2026.

Geography

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