Phylogenomic Framework and Virulence Genes of 359 Emerging E. coli O118 Genomes

A genomic analysis of 359 Shiga toxin-producing Escherichia coli (STEC) O118 genomes, including 357 publicly available draft genomes and two closed reference strains. The dataset profiles virulence factors, resistance traits, and phylogenetic relationships across ten H-antigen types. It was authored by Irvin Rivera and last updated on May 15, 2026.

Use Cases

• Phylogenetic clustering analysis based on multilocus sequence typing of 4,160 shared genes.
• Characterizing virulence gene profiles, including Shiga toxin subtypes (stx1a, stx2a, stx2b, stx2c, stx2f) and eae subtypes.
• Investigating correlations between H-antigen types and specific virulence factors like the locus of enterocyte effacement (LEE).
• Identifying horizontally acquired genetic elements, such as pathogenicity islands and antibiotic resistance loci.

Strengths

• Includes 359 O118 STEC genomes, providing a substantial sample size for analysis.
• Contains two closed, high-quality reference genomes alongside 357 draft genomes for comparative study.
• Profiles ten different H-antigen types and multiple Shiga toxin subtypes, capturing genetic diversity.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is relatively small at 9.5 MB, which may limit the scope of certain analyses.

Provenance

Source

figshare

Collection Method

Genomic sequencing and analysis of publicly available genomes and two closed strains from the author's collection.

Freshness

Last updated 2026-05-15 09:41:09; freshness should be verified.