Bulk RNA-sequencing data from archival FFPE tissues of term placentas. The dataset includes 20 pregnancies complicated by fetal left ventricular outflow tract obstruction (LVOTO) and 10 healthy controls. It was authored by Durga Udayakumar and harvested by the Texas Data Repository.
Use Cases
- Identify differentially expressed genes based on RNA-seq data from LVOTO and control placentas.
- Associate placental transcriptomic states with fetal LVOTO based on the described cohort.
- Investigate cellular state changes in placental pathologies linked to LVOTO based on the dataset's description.
Strengths
- Includes 30 total samples (20 LVOTO cases and 10 healthy controls).
- Data is derived from term placentas, providing a specific developmental stage.
- Uses archival FFPE tissues, a common and stable sample preservation method.
Limitations
- Column-level documentation is absent; field semantics must be inferred after download.
- Row count is unknown, which may limit suitability assessment.
- Freshness should be verified; the last updated date is 2026-05-18.
Provenance
- Source
- Texas Data Repository Harvested Dataverse
- Collection Method
- Bulk RNA-sequencing of archival FFPE placental tissues.
- Freshness
- Last updated 2026-05-18 04:10:56.