Eugenia Florida Leaf Compounds with Antioxidant and Cytotoxic Bioactivity

Twenty-nine compounds from Eugenia florida leaves were fully identified, including triterpenic and phenolic acids. The study measured antioxidant activity, with the most active fractions reaching half the potency of a TBHQ control, and cytotoxicity against two cancer cell lines. This dataset originates from a research paper by Priscila Freitas Santos, analyzing fractions from ethanol extraction.

Use Cases

• Predicting antioxidant potential based on compound classes and extraction fractions.
• Modeling cytotoxicity against specific cancer cell lines like K562 and SK-Mel-28.
• Correlating mass spectrometry fragmentation patterns with identified chemical structures.

Strengths

• Twenty-nine compounds were fully identified with specific analytical techniques.
• Bioactivity results include quantitative EC50 and IC50 values for different fractions.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Last update date is unknown; freshness unverified.

Provenance

Source

Priscila Freitas Santos via paperswithcode

Collection Method

Chemical extraction, fractionation, and analysis by GC-MS and UFLC-DAD-ESI-Ion Trap-MSn.