In Vitro Polyphenol Effects on Enzyme Inhibition and Bioavailability

A collection of processed and raw data from an in vitro study investigating the effects of polyphenols like quercetin, kaempferol, and isoquercetin. The data was used to analyze their ability to inhibit α-amylase and α-glucosidase enzymes and assess bioavailability in Caco-2 cell monolayers. Row and column counts are not specified.

Use Cases

• Analyze α-amylase and α-glucosidase inhibition data for different polyphenol combinations to identify synergistic effects.
• Model bioavailability outcomes in Caco-2 monolayers based on polyphenol type and concentration.
• Reproduce statistical analyses and figures from the associated manuscript using the provided GraphPad Prism files.

Strengths

• Data is directly associated with a specific research study and manuscript preparation.
• Includes both raw and processed data formats, facilitating reproducibility and secondary analysis.
• Covers multiple polyphenol compounds (quercetin, kaempferol, isoquercetin) and their combinations.

Limitations

• Dataset size, row count, and specific column structure are unknown, limiting assessment of analytical scope.
• Data is derived from a single in vitro study, which may not directly translate to in vivo biological effects.
• The description mentions 'preperation' of the manuscript, suggesting potential for typographical errors in metadata.

Provenance

Source

DataverseNL Harvested Dataverse

Collection Method

In vitro laboratory study measuring enzyme inhibition and bioavailability in cell models.

Freshness

Last updated on 2026-02-23.