Toxoplasma Gondii Seroprevalence in Sickle Cell Disease Patients in Ghana

Ghanaian patients with sickle cell disease (SCD) attending a clinic at Ho Teaching Hospital were surveyed for Toxoplasma gondii infection. The dataset contains results from 156 participants, with sociodemographic information, cat ownership, meat consumption habits, and blood transfusion history linked to serological test results (RDT and ELISA). The study was authored by Verner N. Orish and last updated in April 2026.

Use Cases

• Assessing the association between blood transfusion history and Toxoplasma gondii seropositivity based on ELISA and RDT results.
• Analyzing the relationship between age and infection prevalence among sickle cell disease patients.
• Investigating potential risk factors like cat ownership and consumption of poorly cooked meat for Toxoplasma gondii infection.
• Comparing diagnostic test performance (Rapid Diagnostic Test vs. Enzyme-linked Immunosorbent Assay) for serological detection.

Strengths

• Dataset includes results from 156 sickle cell disease patients, with 124 (79.5%) having HbSS genotype.
• Contains paired test results from two diagnostic methods (RDT and ELISA) for 60 and 83 positive cases respectively.
• Links clinical serology data with patient sociodemographics and risk factor questionnaires.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data is limited to a single clinic in Ghana's Volta Region, which may affect generalizability.

Provenance

Source

figshare, authored by Verner N. Orish.

Collection Method

Cross-sectional study using questionnaires and blood sample collection with RDT and ELISA testing.

Time Range

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Freshness

Last updated 2026-04-03 17:49:49; freshness should be verified.

Geography

Ho Teaching Hospital, Volta Region, Ghana.