Magnesium Trial in Acute Asthma: Pediatric Emergency Department Study Data

Suzanne Schuh's dataset contains results from a randomized double-blind placebo-controlled trial conducted across 6 Canadian pediatric emergency departments. The trial enrolled 192 otherwise healthy children aged 2–17 years with acute asthma to test the effect of early intravenous magnesium sulfate therapy versus placebo. The data was last updated on 2026-06-03 and is shared under a CC-BY-4.0 license.

Use Cases

• Evaluate the efficacy of intravenous magnesium sulfate based on Pediatric Respiratory Assessment Measure (PRAM) scores at 2 hours post-intervention.
• Analyze secondary outcomes such as hospitalization rates and asthma re-visits within 72 hours.
• Compare changes in vital signs over a 3-hour observation period between treatment and placebo groups.
• Assess the statistical power of a trial designed to detect a PRAM score difference of ≥1.0 point.

Strengths

• Data originates from a multi-center randomized controlled trial across 6 sites, enhancing generalizability.
• The study design is explicitly defined as double-blind and placebo-controlled.
• Sample size of 192 patients was calculated for 80% power to detect a specified effect.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 5.5 KB, indicating limited scope.

Provenance

Source

Suzanne Schuh via figshare.

Collection Method

Data collected from a randomized controlled clinical trial.

Freshness

Last updated 2026-06-03 17:52:39; freshness should be verified.

Geography

6 pediatric emergency departments in Canada.