Ubiquitylated Peptides in Mtb-Infected Macrophages Identified by Mass Spectrometry

Over 46,000 ubiquitylated peptides identified via mass spectrometry in Mycobacterium tuberculosis-infected macrophages. The data includes roughly 400 peptides with CBL-dependent ubiquitylation, revealing potential substrates for the ubiquitin ligase CBL. This dataset was authored by Tina Truong and last updated in March 2026.

Use Cases

• Identify potential CBL substrates based on CBL-dependent ubiquitylation data.
• Analyze ubiquitin-mediated signaling events in response to Mtb infection.
• Investigate the role of the FAF2 adapter protein in immune signaling downstream of CBL.
• Study the regulation of antiviral versus antibacterial response genes in infected macrophages.

Strengths

• Contains over 46,000 identified ubiquitylated peptides.
• Includes roughly 400 peptides with specifically CBL-dependent ubiquitylation.
• Data is openly available under a CC-BY-4.0 license.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small (9.5 KB), indicating limited scope.

Provenance

Source

figshare

Collection Method

Mass spectrometry analysis of Mtb-infected macrophages.

Time Range

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Freshness

Last updated 2026-03-17 17:36:51; freshness should be verified.

Geography

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