Venous Thrombosis Recurrence Risk and Thrombophilia Impact Study

A retrospective longitudinal study by Héla Baccouche of Hôpital La Rabta evaluated the impact of inherited thrombophilia on treatment decisions and recurrence risk in venous thromboembolism (VTE). The study includes 190 patients with confirmed VTE referred for thrombophilia screening between January 2011 and December 2016. Results indicate inherited thrombophilia was confirmed in 27.5% of patients and was not associated with a higher risk of VTE recurrence after treatment withdrawal.

Use Cases

• Predicting VTE recurrence risk based on patient characteristics and thrombophilia status.
• Analyzing the association between inherited thrombophilia and long-term anticoagulation treatment decisions.
• Modeling the cumulative incidence of VTE recurrence over a 24-year period stratified by thrombophilia presence.

Strengths

• Study includes 190 patient records with confirmed VTE diagnoses.
• Provides specific metrics: 27.5% of patients had confirmed inherited thrombophilia, and 13.7% experienced VTE recurrence.
• Reports a 24-year cumulative incidence of recurrence (9% with IT vs. 14% without).

Limitations

• Row count and column-level documentation are unknown; field semantics must be inferred after download.
• Data may reflect temporal and institutional bias inherent to a single-center retrospective study from 2011-2016.

Provenance

Source

Héla Baccouche, Hôpital La Rabta

Collection Method

Retrospective longitudinal study of patients referred for inherited thrombophilia screening.

Time Range

January 2011 - December 2016