Pregnancy Outcomes of Frozen-Thawed Embryo Transfer Cycles, 24,422 Cycles

A retrospective cohort study from two reproductive centers affiliated with Peking University. It analyzes 24,422 frozen-thawed embryo transfer cycles recorded between January 2015 and May 2018. The research database includes maternal characteristics and measures outcomes such as biochemical pregnancy, clinical pregnancy, miscarriage, and live birth.

Use Cases

• Compare pregnancy success rates based on the number and stage of embryos transferred.
• Analyze risks of adverse neonatal outcomes like twin births and preterm births associated with different transfer methods.
• Model the relationship between maternal characteristics and clinical pregnancy or live birth outcomes.
• Evaluate the trade-offs between higher pregnancy rates and higher complication risks in blastocyst versus cleavage embryo transfers.

Strengths

• Large sample size of 24,422 frozen-thawed embryo transfer cycles.
• Data spans over three years, from January 2015 to May 2018.
• Includes key clinical outcome measures: biochemical pregnancy, clinical pregnancy, miscarriage, maternal complications, and live birth.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Data may reflect geographic and institutional bias inherent to the two specific centers studied.
• Row count for specific subgroups is unknown, which may limit suitability assessment for granular analysis.

Provenance

Source

Peking University

Collection Method

Retrospective analysis of clinical ART databases from two affiliated hospitals.

Time Range

January 2015 to May 2018

Geography

China (implied by affiliation with Peking University)