RNA sequencing data from galt knockout and wild-type zebrafish embryos, larvae, and juveniles investigates prenatal contributions to Classic Galactosemia pathology. Differentially expressed genes were analyzed using KEGG and GO enrichment, and metabolic pathway changes were assessed with MetaPhOR. The dataset was authored by Naomi Vos and last updated on June 15, 2026.
Use Cases
- Identify differentially expressed genes in a Classic Galactosemia model based on RNA sequencing data.
- Perform pathway enrichment analysis based on KEGG and GO term results.
- Investigate developmental trajectory of transcriptional signatures based on data from embryos, larvae, and juveniles.
- Study metabolic pathway alterations in a galt knockout model based on MetaPhOR analysis.
Strengths
- Data includes RNA sequencing results from multiple developmental stages: embryos, larvae, and juveniles.
- Analysis includes both KEGG and GO enrichment for differentially expressed genes.
Limitations
- Column-level documentation is absent; field semantics must be inferred after download.
- Row count is unknown, which may limit suitability assessment.
Provenance
- Source
- DataverseNL Harvested Dataverse
- Collection Method
- RNA sequencing performed on galt knockout and wild-type zebrafish.
- Freshness
- Last updated 2026-06-15 06:10:36.