PREPARATION, PHYSICOCHEMICAL CHARACTERIZATION AND CONTROLLED RELEASE OF GALACTOMANNAN MICR

84% encapsulation efficiency was achieved for allantoin in galactomannan microparticles prepared by spray drying. The spherical particles had an average size of 2.84 ± 0.41 µm and provided a controlled drug release over 6 hours, meeting Brazilian Pharmacopoeia standards. This research dataset by Hilana B. M. Frota characterizes the microparticles using IR, SEM, thermal analysis, and X-ray diffraction.

Use Cases

• Modeling controlled drug release kinetics based on the 6-hour release profile data
• Analyzing the relationship between particle morphology and encapsulation efficiency based on SEM and efficiency results
• Studying the impact of polymer encapsulation on drug crystallinity based on X-ray diffraction findings

Strengths

• Encapsulation efficiency is quantified at approximately 84%
• Particle size is precisely reported as 2.84 ± 0.41 µm
• Release profile is validated against a pharmacopoeia standard over a 6-hour period

Limitations

• Row count and specific data file structure are unknown
• Column-level documentation is absent; field semantics must be inferred after download
• Last update date is unknown; freshness unverified

Provenance

Source

Hilana B. M. Frota

Collection Method

Data likely originates from laboratory experiments involving spray drying, spectroscopy, and thermal analysis.