Prevalence of Otoneurological Symptoms in Children with Congenital Hypothyroidism

105 children aged 5 years or more diagnosed with congenital hypothyroidism were studied via parent/caregiver questionnaires and medical records. 72.4% of subjects showed symptoms related to vestibulocochlear disorder, with dizziness/vertigo at 56.2%, hearing loss at 43.8%, and tinnitus at 12.4%. The pilot study by Caio Leônidas De Andrade found statistical correlations between symptoms and clinical factors like neonatal screening age.

Use Cases

• Correlating otoneurological symptom prevalence with clinical factors like age of neonatal screening based on the study's findings
• Analyzing the association between congenital hypothyroidism and specific symptoms like dizziness, hearing loss, and tinnitus based on the reported statistical correlations
• Investigating demographic or clinical patterns within a pediatric patient cohort diagnosed with congenital hypothyroidism

Strengths

• Dataset is based on a sample of 105 children, providing a concrete cohort size
• Includes specific prevalence percentages for symptoms: 72.4% for vestibulocochlear disorder, 56.2% for dizziness/vertigo, 43.8% for hearing loss, and 12.4% for tinnitus
• Reports statistical correlations (e.g., p=0.016 for hearing loss) and exposure factors (PR=0.49) from the analysis

Limitations

• Row count and column-level documentation are unknown, which may limit suitability assessment
• Last update date is unknown; freshness unverified
• Data may reflect the specific cohort and methodology of a single pilot study, limiting generalizability

Provenance

Source

Caio Leônidas De Andrade

Collection Method

Exploratory sectional descriptive study using structured questionnaires for parents/caregivers and clinical/laboratory data from medical records.