Mouse ILC3 Subset Proportions in NEC with Autophagy and Metabolic Interventions

Flow cytometry data from an experimental study on necrotizing enterocolitis in mice. The dataset contains measurements of group 3 innate lymphoid cell (ILC3) proportions and counts under conditions of autophagy deficiency and metabolic interventions. Author Junyu He published the data on figshare in April 2026.

Use Cases

• Compare ILC3 subset proportions based on autophagy status mentioned in the description
• Analyze the effect of lactate supplementation on ILC3 counts as described in the experimental groups
• Evaluate the impact of fatty acid oxidation inhibition (etomoxir) on ILC3 populations
• Model the relationship between autophagy deficiency and ILC3 dynamics in a mouse NEC model

Strengths

• 7 biological replicates per experimental group, providing statistical power
• Data acquired using a CytoFLEX S flow cytometer with a detailed antibody staining panel
• Statistical analysis performed using one-way ANOVA with Tukey's post-hoc test

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment

Provenance

Source

figshare

Collection Method

Experimental flow cytometry data from genetically modified C57BL/6 mice subjected to standardized NEC induction.

Time Range

Experimental data collection date is not specified.

Freshness

Last updated 2026-04 16 02:32:40; freshness should be verified

Geography

Laboratory study; geographic location is not specified.