Processed Proteomic and Phosphoproteomic Data for Cardiac Beta-Adrenergic Signaling Study

127.2 MB of processed proteomic and phosphoproteomic data from a study investigating nitric oxide regulation of cardiac beta-adrenergic signaling. The dataset contains quantitative protein and phosphopeptide measurements analyzed with Spectronaut and MSFragger, supporting findings on NOS1 and PKA signaling. It was authored by Sherif M. F. M. Bahriz and last updated in May 2026.

Use Cases

• Analyze protein-level quantification changes based on data-independent acquisition (DIA) proteomics
• Investigate phosphopeptide dynamics in cardiac signaling based on data-dependent acquisition (DDA) phosphoproteomics
• Study nitric oxide-mediated regulation of PKA signaling based on quantitative protein and phosphopeptide measurements
• Validate computational models of beta-adrenergic signaling pathways based on processed mass spectrometry data

Strengths

• Data processed with established analysis tools Spectronaut and MSFragger
• Dataset size of 127.2 MB indicates substantial processed quantitative measurements
• Explicitly supports findings from an associated peer-reviewed manuscript

Limitations

• Raw mass spectrometry data are not available, limiting reproducibility of processing steps
• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment

Provenance

Source

figshare

Collection Method

Data generated via mass spectrometry (DIA for proteomics, DDA for phosphoproteomics) and processed with Spectronaut and MSFragger.

Freshness

Last updated 2026-05-14 16:36:19