L-Serine Biofilm Induction in Gut Enterococcus

L-serine released from Bacillus thuringiensis protoxin reprograms Enterococcus bacteria to form robust biofilms, accelerating host mortality. The dataset likely contains metabolomic, transcriptomic, and phenotypic analyses supporting this finding. It was authored by Zeyu Wang and uploaded to figshare in April 2026.

Use Cases

• Analyze transcriptomic pathways like phosphotransferase system and LPXTG-motif adhesion proteins upregulated by L-serine exposure.
• Correlate metabolomic L-serine levels with phenotypic biofilm formation metrics in Enterococcus.
• Model the relationship between stress resistance state features and systemic translocation or host mortality outcomes.

Strengths

• Data integrates metabolomic, transcriptomic, and phenotypic analyses from a controlled experimental study.
• Results reveal a specific molecular mechanism linking a protoxin-derived metabolite (L-serine) to bacterial pathogenicity.

Limitations

• Dataset size is 339.5 KB, indicating a limited scope likely focused on a specific experimental series.
• Unknown row count suggests the dataset may contain summarized results rather than raw experimental data.
• Geographic and host organism coverage is unspecified, limiting generalizability.

Provenance

Source

Zeyu Wang via figshare.

Collection Method

Integrated metabolomic, transcriptomic, and phenotypic analyses from laboratory experiments.

Freshness

Last updated in April 2026.