Simultaneous Single-Cell Calcium Imaging and Whole-Brain fMRI in Awake Mice

2.9 GB of simultaneous cellular calcium activity and whole-brain BOLD fMRI recordings from awake mice. The data, published by Rik Ubaghs in 2026, was collected using an MRI-compatible single-photon microscope. It reveals spatially specific relationships between genetically defined neurons and the surrounding vasculature.

Use Cases

• Modeling the relationship between neural activity and BOLD signals based on neuron proximity to blood vessels.
• Analyzing how local neural activity correlates with BOLD responses in connected brain regions.
• Developing tools for bridging cellular-resolution and whole-brain measurements of brain function.

Strengths

• Data size is 2.9 GB, indicating a medium-scale dataset.
• Simultaneously captures two distinct modalities: cellular calcium imaging and whole-brain BOLD fMRI.
• Recordings are from awake mice, which likely provides more behaviorally relevant neural activity.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect methodological bias inherent to the specific experimental setup.

Provenance

Source

Rik Ubaghs via figshare

Collection Method

Collected using an MRI-compatible single-photon microscope enabling simultaneous recordings.

Freshness

Last updated 2026-05-03 17:20:00.