Randomized Trial of a Catastrophe Mindset Intervention for Depression and Immune Response

United States data from a 2022-2023 randomized controlled trial with 548 adult participants. The study tests a 'Catastrophes can be Opportunities' mindset intervention against a control task, measuring effects on post-traumatic growth, depression, and immune dysregulation. It includes two cohorts, one providing blood samples at three time points.

Use Cases

• Analyze intervention effects on depression scores and self-esteem measures between the mindset and control groups.
• Correlate immune dysregulation markers from blood samples with questionnaire responses on attitudes and perceived growth.
• Model predictors of post-traumatic growth using participant demographics, mental health history, and intervention condition.
• Compare mental health trajectories between the 'physio' and 'non-physio' cohorts over the study's time points.

Strengths

• Data from a randomized controlled trial design with 548 participants, allowing for causal inference.
• Includes physiological data from blood samples for a subset of participants, enabling biomarker analysis.
• Intervention is structured with specific video content and writing prompts detailed in the study protocol.

Limitations

• Sample is limited to U.S. adults who completed four previous COVID-19 surveys, introducing selection bias.
• The study focuses on a specific, brief intervention, limiting generalizability to other therapeutic approaches.
• Unknown sample size for the 'physio' cohort providing blood samples, complicating power analysis for biomarker studies.

Provenance

Source

ICPSR Harvested Dataverse, authored by Jesse Barrera.

Collection Method

Randomized controlled trial with participants recruited from a prior longitudinal COVID-19 survey panel.

Time Range

2022-2023

Freshness

Data archived in 2026, covering a study conducted in 2022-2023.

Geography

United States