C52: CSF1R Inhibitor Structures for Acute Liver Injury Treatment

A figshare dataset by Xue Yuan, last updated April 2026, containing molecular structure data for a series of colony-stimulating factor 1 receptor (CSF1R) inhibitors. The data, stored in PDB format, relates to compounds like C52, which were designed for treating acetaminophen-induced acute liver injury. The dataset size is 365.9 KB.

Use Cases

• Structure-activity relationship analysis based on the series of CSF1R inhibitors described.
• Molecular docking studies based on the PDB structure files for compounds like C52.
• Kinome-wide selectivity profiling for new drug candidates based on the described selective profile.
• Preclinical efficacy modeling for acute liver injury treatments based on the described in vivo results.

Strengths

• Dataset includes specific molecular structure data (PDB files) for a named compound, C52.
• License (CC-BY-NC-4.0) permits non-commercial reuse with attribution.
• Last update timestamp (2026-04-23) is precisely recorded.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The 365.9 KB size indicates a very limited scope, likely containing only a few molecular structures.

Provenance

Source

figshare, author Xue Yuan.

Collection Method

Likely generated through structure-guided optimization and experimental validation as described.

Freshness

Last updated 2026-04-23 19:34:50; freshness should be verified.