C4-VG7: Anti-ESKAPE Lipopeptide Design and Efficacy Data

Junji Zhang's dataset on figshare, last updated May 28, 2026, describes the rational design and testing of C4-VG7, a lipopeptide engineered from a marine conotoxin. The 13.8 KB dataset likely contains experimental results showing the compound's broad-spectrum activity against multidrug-resistant ESKAPE pathogens and its efficacy in murine infection models.

Use Cases

• Train predictive models for antimicrobial activity based on peptide sequence and lipid modification features mentioned in the description
• Analyze structure-activity relationships for engineered lipopeptides against ESKAPE pathogens
• Benchmark new compound designs against the reported MIC values and in vivo efficacy data

Strengths

• Dataset is small (13.8 KB), facilitating quick download and inspection.
• Description provides specific details on the lead candidate's MIC (≈1 μM) and in vivo model results.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Likely contains experimental results from the rational design and testing of the C4-VG7 lipopeptide.

Freshness

Last updated 2026-05-28 10:04:08; freshness should be verified.