Raw Data: Molecular Mechanisms of HBV-Associated Liver Cancer

1.7 GB of raw data supporting research on Hepatitis B virus (HBV) and hepatocellular carcinoma (HCC). The dataset, authored by Lan Huang and last updated on 2026-05-27, investigates the S-nitrosylation of host factor DDX3 as a mechanism of immune evasion. It is shared under a CC-BY-4.0 license via figshare.

Use Cases

• Investigate the role of iNOS upregulation in HBV immune evasion based on the described mechanism.
• Analyze the functional impact of DDX3 S-nitrosylation at Cys223 on antiviral activity.
• Validate the tumor-suppressive effects of the non-nitrosylatable DDX3C223A mutant.
• Explore therapeutic strategies targeting post-translational modifications in HBV-associated HCC.

Strengths

• Dataset size is 1.7 GB, indicating substantial raw data volume.
• License is clearly defined as CC-BY-4.0, facilitating open reuse.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

Lan Huang

Freshness

Last updated 2026-05-27 07:20:07; freshness should be verified.