TWEAK/Fn14 Pathway Data for Cutaneous Candida albicans Infection

Raw data and full-size Western blots support a study on the TWEAK/Fn14 pathway's role in early host defense against skin Candida albicans infection. The dataset includes quantitative analysis data and original uncropped blot images from experiments using keratinocyte assays and a murine intradermal infection model. Author xiaoyu wang published this dataset on figshare under a CC-BY-4.0 license, with a last update timestamp of 2026-04-23.

Use Cases

• Analyze cytokine expression (IL-1β, IL-8, IL-17A, HBD-2) based on data from keratinocyte assays.
• Investigate MAPK activation patterns linked to TLR4 and Fn14 pathway interactions described in the study.
• Validate Western blot results using the provided full-size, uncropped original images.
• Model early infection control metrics, such as fungal burden and lesion size, based on in vivo mouse model data.

Strengths

• Includes original, uncropped Western blot images, supporting result verification.
• Quantitative data underpins statistical analyses for a peer-reviewed study.
• Covers multiple experimental layers: in vitro keratinocyte assays and an in vivo murine infection model.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data scale and file formats are unspecified in the provided metadata.

Provenance

Source

figshare

Collection Method

Experimental data from keratinocyte-based assays and a murine intradermal infection model.

Freshness

Last updated 2026-04-23 11:44:37; freshness should be verified.