Wistar Rat Atopic Biomarker Changes After Porphyromonas gingivalis LPS Exposure

16 Wistar rats were used in an experimental study to measure IgE and IgG4 levels after exposure to Porphyromonas gingivalis lipopolysaccharide. The data likely contains periodic measurements of IgE, IgG4, and the IgG4/IgE ratio from sera taken before and after exposure. This dataset was contributed by Sindy Cornelia Nelwan and is available via paperswithcode.

Use Cases

• Modeling temporal changes in IgE and IgG4 levels based on LPS dosage groups described in the study.
• Analyzing the relationship between IgG4/IgE ratio and atopic response modulation as discussed in the results.
• Training classifiers to differentiate biomarker profiles between control and LPS-exposed groups mentioned in the methods.

Strengths

• Experimental design includes 16 subjects across 4 distinct dosage groups, as specified in the methods.
• Measures specific biomarkers (IgE, IgG4) at multiple time points (day-4 and day-11) as reported in the results.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Last update date is unknown; freshness unverified.

Provenance

Source

Sindy Cornelia Nelwan via paperswithcode

Collection Method

Experimental study involving injection of Porphyromonas gingivalis LPS into Wistar rats and serum collection.