Mouse Stroke Model Data: Behavioral, Neuronal, and Glial Effects

16.2 GB of raw data supporting a 2025 study in Translational Stroke Research by Sidra Tabassum. The dataset contains behavioral, neuronal, and glial measurements from three mouse stroke models: subarachnoid hemorrhage, transient middle cerebral artery occlusion, and photothrombotic stimulation. It includes immunohistochemical analysis of dopaminergic markers and glial activation in limbic brain regions.

Use Cases

• Compare motor and cognitive deficits across different stroke models based on the described behavioral assays.
• Analyze region-specific dopaminergic vulnerability in the hippocampus based on tyrosine hydroxylase and NeuN overlap data.
• Investigate chronic inflammatory responses in the amygdala based on astrocytic and microglial activation metrics.
• Correlate affective behavioral changes with neuronal and glial alterations in limbic regions.

Strengths

• Dataset is 16.2 GB, indicating a substantial volume of raw data.
• Data is associated with a peer-reviewed manuscript published in Translational Stroke Research in 2025.
• The description details specific experimental models (SAH, tMCAO, PTS) and measured outcomes (behavior, immunohistochemistry).

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is a single ZIP file; internal structure and specific file formats are not detailed.

Provenance

Source

figshare, authored by Sidra Tabassum.

Collection Method

Likely contains experimental data from mouse models of stroke, including behavioral testing and immunohistochemical analysis.

Freshness

Last updated 2026-05-29 18:19:59