Glucose Concentration Effects on Mitophagy in Human iNeurons, 163.8 GB Dataset

Underlying datasets for the O'Callaghan et al., 2026 manuscript on glucose concentration and PINK1-dependent mitophagy. The 163.8 GB collection includes raw confocal microscopy images, RT-qPCR data, tabular data for all graphed results, and uncropped blots. It was authored by Benjamin O'Callaghan and published on figshare in June 2026.

Use Cases

• Replicate statistical analyses based on the provided tabular data for all graphed results.
• Re-analyze raw confocal microscopy images to quantify mitophagy markers.
• Validate RT-qPCR results using the provided .rdml files.
• Inspect uncropped western blots for protein expression data.

Strengths

• Dataset size is 163.8 GB, indicating a substantial volume of raw experimental data.
• Includes multiple raw data modalities: confocal images, RT-qPCR files, and tabular data.
• Released under a permissive CC-BY-4.0 license for reuse.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

Benjamin O'Callaghan

Collection Method

Experimental data from a study on human induced pluripotent stem cell (iPSC)-derived neurons.

Freshness

Last updated 2026-06-04 16:14:01; freshness should be verified.