Pseudomonas Aeruginosa Glutathione Peroxidase Virulence Data from Mouse Model

Research data from a study investigating the role of bacterial glutathione peroxidase in Pseudomonas aeruginosa virulence under hyperuricemic conditions. The dataset, authored by Jadye da Silva Cordeiro and last updated in May 2026, includes results from in vitro oxidant exposure and in vivo mouse infection models. Findings demonstrate that GPx detoxifies organic hydroperoxides, enhancing bacterial resistance to oxidative killing.

Use Cases

• Modeling bacterial survival under oxidative stress based on susceptibility to hypochlorous acid and hydrogen peroxide.
• Investigating host-pathogen interactions based on neutrophil killing assay results.
• Analyzing virulence factors based on pulmonary bacterial burden and survival data from mouse infection models.
• Studying the impact of hyperuricemia on infection outcomes based on comparative data from normouricemic and induced-hyperuricemic mice.

Strengths

• Data is associated with a peer-reviewed research study with a detailed experimental description.
• The dataset is licensed under CC-BY-4.0, allowing for broad reuse with attribution.
• Files are provided in common document formats (PDF, DOCX) for accessibility.

Limitations

• The dataset is small (848.7 KB), indicating limited scope and likely containing summary results rather than raw experimental data.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for statistical analysis.

Provenance

Source

figshare

Collection Method

Experimental data from in vitro bacterial exposure to oxidants and in vivo mouse infection models, as described in the associated research.

Freshness

Last updated 2026-05-22 11:12:47; freshness should be verified.