Regioselective Synthesis of Carborane-Fused Boralactams via Nitrenoid-Mediated B(4)–H Amid

A dataset from figshare describes a chemical synthesis method for carborane-fused boralactams. The dataset, authored by Hee Chan Noh and last updated in May 2026, includes a 44.8 MB ZIP file. The described method accommodates a broad range of carborane substrates and delivers products in high yields with excellent regioselectivity.

Use Cases

• Training models to predict regioselectivity in carborane amidation reactions based on substrate structure.
• Screening potential bioisosteric replacements for oxindoles in drug discovery based on geometric mimicry.
• Analyzing the scope and limitations of Ir-catalyzed intramolecular B–H amidation reactions.

Strengths

• The described method accommodates a broad range of carborane substrates, including meta- and para-carborane derivatives.
• The transformation generally delivers the corresponding products in high yields with excellent regioselectivity.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for large-scale modeling.

Provenance

Source

figshare

Collection Method

Experimental chemical synthesis

Freshness

Last updated 2026-05-11 13:03:52; freshness should be verified.