Regioselective Synthesis of Carborane-Fused Boralactams via Nitrenoid-Mediated B(4)–H Amid

He Chan Noh published a dataset on figshare in May 2026 describing the regioselective Ir-catalyzed intramolecular B(4)–H amidation of ortho-carborane-tethered dioxazolones. The dataset likely contains experimental results for synthesizing carborane-fused boralactams, which mimic oxindoles, under mild conditions. It is a 13.1 MB ZIP file licensed under CC-BY-NC-4.0.

Use Cases

• Train models to predict regioselectivity in carborane B–H functionalization reactions based on substrate structure.
• Benchmark computational methods for modeling Ir-catalyzed amidation reactions described in the paper.
• Analyze structure-activity relationships for oxindole bioisosteres based on the geometric features of the synthesized boralactams.

Strengths

• Dataset size is 13.1 MB, indicating a substantial amount of raw data.
• The described synthesis accommodates a broad range of carborane substrates, including meta- and para-carborane derivatives.
• The described method delivers products in high yields with excellent regioselectivity.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

He Chan Noh

Collection Method

Likely contains experimental data from the reported regioselective Ir-catalyzed intramolecular B(4)–H amidation reactions.

Freshness

Last updated 2026-05-11 13:03:54; freshness should be verified.