Regioselective Synthesis of Carborane-Fused Boralactams via B(4)–H Amidation

Hee Chan Noh published experimental data on figshare in May 2026. The dataset supports a report on an iridium-catalyzed intramolecular B(4)–H amidation of ortho-carborane-tethered dioxazolones. It includes results for meta- and para-carborane derivatives, yielding products that mimic oxindole geometry.

Use Cases

• Training models for predicting regioselectivity in carborane amidation reactions based on substrate structure
• Benchmarking synthetic methods for boralactam production based on reported high yields
• Studying geometric features of oxindole bioisosteres based on the described structural mimicry

Strengths

• Dataset size is 38.4 MB, indicating a substantial amount of supporting data.
• The described method accommodates a broad range of carborane substrates, including meta- and para-derivatives.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.

Provenance

Source

Hee Chan Noh via figshare

Collection Method

Experimental synthesis data from a published chemical study.

Freshness

Last updated 2026-05-11 13:03:49; freshness should be verified.