Risk Factors for Retinopathy of Prematurity in Very Low Birth Weight Neonates

A clinical study dataset investigating the relationship between anemia, red blood cell transfusions, and the development of Retinopathy of Prematurity (ROP) in very premature, very low birth weight neonates. The dataset, created by Raluca Mihetiu and shared under a CC-BY-4.0 license, includes a binary logistic regression model adjusting for gestational age, sepsis, and respiratory distress syndrome. The model indicates a significant association, with an adjusted odds ratio of 4.812 for transfusion risk.

Use Cases

• Validate the statistical association between red blood cell transfusions and ROP risk based on the described regression model.
• Replicate the study's logistic regression analysis adjusting for gestational age and illness severity factors.
• Explore potential interactions between anemia, transfusions, and other clinical risk factors for ROP mentioned in the description.

Strengths

• Dataset includes a validated statistical model with a Nagelkerke R-squared of 0.358 and p < 0.001.
• Analysis controls for key clinical confounders like gestational age, sepsis, and respiratory distress syndrome.
• The dataset is openly shared under a permissive CC-BY-4.0 license.

Limitations

• The dataset is very small at 6.7 KB, indicating limited scope or a small sample size.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for certain analyses.

Provenance

Source

figshare

Collection Method

Likely contains clinical study data from a medical research project.

Time Range

null

Freshness

Last updated 2026-04-23 07:36:27; freshness should be verified.

Geography

null