A replication dataset for a study using a custom protein microarray with over 70 merozoite antigens to screen serum samples from a controlled human malaria infection trial. The data was used to identify antigen combinations associated with clinical immunity to falciparum malaria. The dataset was authored by Rodney Ogwang and last updated on April 29, 2026.
Use Cases
- Identify predictive biomarkers for clinical immunity based on serum antibody profiles.
- Analyze associations between specific merozoite antigens and protection from malaria symptoms.
- Validate findings from the original manuscript using the provided replication data.
Strengths
- Data is derived from a controlled human infection study, a high-standard experimental model.
- Analysis is based on a custom protein microarray screening over 70 distinct merozoite antigens.
Limitations
- Column-level documentation is absent; field semantics must be inferred after download.
- Row count is unknown, which may limit suitability assessment for large-scale analyses.
Provenance
- Source
- Biosciences Dataverse
- Collection Method
- Serum samples screened using a custom protein microarray from a controlled human malaria infection study.
- Freshness
- Last updated 2026-04-29 16:48:06; freshness should be verified.