Harvard Dataverse hosts replication data for a study on the TREM2 R47H variant in Alzheimer's disease. The dataset contains raw data files and R code needed to recreate figures from the associated paper. Author Gina Faraci uploaded the data, which was last updated on May 1, 2026.
Use Cases
- Replicate statistical analyses and visualizations based on the provided raw data and R code.
- Conduct independent pathway analysis by uploading the processed output to tools like MetaboAnalyst.
- Investigate the liver-plasma-brain axis dyshomeostasis mentioned in the study description.
- Validate findings related to the TREM2 R47H variant in the 5xFAD mouse model.
Strengths
- Includes the raw data and R code necessary for figure generation, supporting reproducibility.
- Associated with a specific, peer-reviewed research study on Alzheimer's disease.
Limitations
- Description metadata is limited; actual data quality requires manual inspection after download.
- Column-level documentation is absent; field semantics must be inferred after download.
Provenance
- Source
- Harvard Dataverse, author Gina Faraci.
- Collection Method
- Data generated as part of a research study on Alzheimer's disease mouse models.
- Time Range
- null
- Freshness
- Last updated 2026-05-01 15:45:45; freshness should be verified.
- Geography
- null