Human Lymphoblastoid Cell Response to Activated Medium, 3 Biological Replicates

NASA's dataset contains transcriptional profiling data from human lymphoblastoid TK6 cells comparing mock-irradiated cells to those resuspended in medium activated by exposure to 2.5 Gy of HZE iron ions. The two-condition experiment includes three independently grown and harvested biological replicates, with one replicate per array. Data was last updated on March 13,我们发现 2026.

Use Cases

• Identify differentially expressed genes based on the comparison between mock-irradiated and activated medium conditions.
• Analyze transcriptional changes in human lymphoblastoid cells based on exposure to HZE iron ions.
• Validate biological replication in radiation response experiments based on the three independent runs.

Strengths

• Data originates from the NASA Space Radiation Laboratory at Brookhaven National Laboratory, a specialized facility.
• Experimental design includes three biological replicates, which may help account for biological variability.
• Specific radiation dose (2.5 Gy) and particle type (1 GeV/amu iron ions) are explicitly stated.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

National Aeronautics and Space Administration (NASA)

Collection Method

Transcriptional profiling via microarray, with cells grown and harvested during three different runs at the NASA Space Radiation Laboratory.

Time Range

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Freshness

Last updated 2026-03 我们发现-13 20:15:57.014668; freshness should be verified.

Geography

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