Lactobacillus acidophilus ATCC 4356 Growth and Stress Response in Simulated Microgravity

NASA research data on the growth, stress survival, and gene expression of the probiotic bacterium Lactobacillus acidophilus ATCC 4356 under low shear modeled microgravity (LSMMG) conditions. The work was conducted using a rotating wall vessel (RWV) to simulate microgravity effects relevant to spaceflight. The dataset was last updated on March 13, 2026.

Use Cases

• Compare probiotic growth rates based on simulated microgravity orientation data.
• Assess bacterial stress tolerance based on survival challenge results.
• Analyze gene expression changes in response to low shear modeled microgravity conditions.
• Evaluate the translation of Earth-based probiotic benefits for potential spaceflight use.

Strengths

• Data originates from NASA, a recognized authority in space research.
• Research focuses on a specific, well-defined probiotic strain (Lactobacillus acidophilus ATCC 4356).
• Experimental design includes a control orientation for comparison with the microgravity analog.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data is provided in a BIN file format, which may require specialized tools to access.

Provenance

Source

National Aeronautics and Space Administration

Collection Method

Experimental data from bacterial cultures grown in a rotating wall vessel (RWV) under low shear modeled microgravity (LSMMG) and control orientations.

Freshness

Last updated 2026-03-13 19:25:06.440130; freshness should be verified.