RNA-seq of Irradiated Host Tumors with Trp53 Null Mammary Tissue and CAPE Diet

RNA sequencing data from tumors derived from irradiated versus sham hosts transplanted with Trp53 null mammary tissue. The dataset was published by the National Aeronautics and Space Administration and was last updated on March 13, 2026. The description indicates irradiated hosts gave rise to more rapidly growing cancers with an immunosuppressive microenvironment, an effect prevented by the dietary supplement CAPE.

Use Cases

• Identify gene expression signatures associated with radiation-induced tumor acceleration based on the RNA-seq data.
• Analyze the impact of the CAPE dietary supplement on tumor growth rate as described.
• Study changes in the immunosuppressive tumor microenvironment mentioned in the dataset description.
• Compare transcriptional profiles between tumors from irradiated and sham-irradiated hosts.

Strengths

• Dataset originates from the National Aeronautics and Space Administration.
• Last update timestamp is precisely recorded as 2026-03-13 19:37:40.102655.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

National Aeronautics and Space Administration

Collection Method

Likely generated from a controlled laboratory experiment involving mouse models.

Freshness

Last updated 2026-03-13 19:37:40.102655; freshness should be verified.