RR1 NASA Validation Flight: Mouse Muscle Transcriptomic and Epigenomic Data

NASA's GeneLab project provides data from the Rodent Research-1 spaceflight experiment. The dataset includes transcriptomic and epigenomic data from mouse extensor digitorum longus muscle and other tissues, harvested from subjects on the International Space Station and stored at -80°C. The data was last updated on March 13, 2026.

Use Cases

• Assess the feasibility of multi-omics analyses on archived spaceflight tissue samples based on the described extraction protocols.
• Investigate spaceflight effects on the mouse transcriptome in new tissue types like the extensor digitorum longus muscle.
• Prioritize future International Space Station crew time for rodent research activities based on the reported scientific value.
• Conduct a systems biology-based analysis of space environment effects using the multi-omics approach described.

Strengths

• Data originates from a controlled NASA spaceflight experiment on the International Space Station.
• Includes multiple tissue types: adrenal glands, quadriceps, gastrocnemius, tibialis anterior, extensor digitorum longus, soleus, eye, and kidney.
• Tissues were preserved using snap-freezing or RNAlater and stored at -80°C for at least a year.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data is stored in a BIN file format, which may require specialized tools for access and analysis.

Provenance

Source

National Aeronautics and Space Administration (NASA), GeneLab project

Collection Method

Tissues harvested from mouse subjects during the first Rodent Research spaceflight experiment on the ISS, then archived and analyzed.

Time Range

Temporal coverage of the experiment is not specified in the provided description.

Freshness

Last updated 2026-03-13 19:21:13.041895; freshness should be verified.

Geography

Data is associated with spaceflight research conducted on the International Space Station.