Nine mouse liver samples were analyzed to study muscle wasting in microgravity. RNA-Seq, BS-Seq, and proteomic profiling were performed on samples from Flight, Ground Control, and Basal Control groups. The data was collected by the National Aeronautics and Space Administration and last updated on the platform in March 2026.
Use Cases
- Identify gene expression changes in liver tissue based on RNA-Seq data mentioned in the description
- Study epigenetic modifications in response to microgravity based on bisulfite sequencing (BS-Seq) data
- Correlate transcriptomic and proteomic profiles to understand post-transcriptional regulation in spaceflight
- Compare biological responses across Flight, Ground Control, and Basal Control experimental groups
Strengths
- Data integrates three omics layers: transcriptomics, epigenomics, and proteomics from the same samples.
- Includes a controlled experimental design with three distinct groups (FLT, GC, BC) and three biological replicates per group.
Limitations
- Column-level documentation is absent; field semantics must be inferred after download.
- Row count is unknown, which may limit suitability assessment.
Provenance
- Source
- National Aeronautics and Space Administration
- Collection Method
- Samples were collected from the Rodent Research-1 (RR-1 CASIS) spaceflight experiment, with on-orbit dissection for the Flight group.
- Freshness
- Last updated 2026-03-05 19:53:24.537656; freshness should be verified.