Graves' Orbitopathy Study: Oncostatin M Expression in Orbital Tissues

Orbital tissues from Graves' orbitopathy patients and healthy controls were analyzed for gene expression. The dataset includes results from quantitative PCR, Western blotting, and Oil Red O staining, authored by Jeong Woo Park and last updated in May 2026. The 1.2 MB collection contains TIF and DOCX files.

Use Cases

• Analyze gene expression patterns for OSM, OSMR, and LIFR based on qPCR data from orbital tissues.
• Investigate inflammatory mediator expression (e.g., IL-6, MCP-1) in cultured orbital fibroblasts based on cytokine treatment experiments.
• Study adipogenic differentiation in orbital fibroblasts based on Oil Red O staining and adipocyte marker levels.
• Evaluate intracellular signaling pathway activation (e.g., JAK2, MAPK) based on Western blotting results.

Strengths

• Includes data from both patient and healthy control tissues, enabling comparative analysis.
• Results from multiple experimental methods (qPCR, Western blot, staining) are described.
• Dataset is openly available under a CC-BY-4.0 license.

Limitations

• Row count and column-level documentation are unknown, limiting suitability assessment.
• The dataset is small at 1.2 MB, which may indicate limited raw data volume.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Experimental analysis of orbital tissues and cultured fibroblasts, as described.

Freshness

Last updated 2026-05-25 05:53:24; freshness should be verified.