Ruthenium Complexes of Atovaquone for Antiplasmodial Activity

Camila Fabbri published a dataset on figshare in April 2026 detailing the synthesis and evaluation of ruthenium complexes of the drug Atovaquone. The data likely contains results from pharmacological evaluations, including structure-activity relationships and efficacy against multiple stages of the Plasmodium parasite. The dataset is 3.7 KB in size and is shared under a CC-BY-NC-4.0 license.

Use Cases

• Modeling structure-activity relationships based on ruthenium oxidation state and coligand properties described in the summary.
• Comparing antiplasmodial activity against asexual and sexual parasite stages, as mentioned in the description.
• Analyzing the accumulation of ruthenium in parasite cells, a key finding noted in the dataset description.
• Evaluating transmission-blocking efficacy for gametocyte and oocyst stages, a highlighted broader effect of the complexes.

Strengths

• Dataset is explicitly licensed as CC-BY-NC-4.0, clarifying reuse terms.
• Description provides specific pharmacological context, such as the comparison of Ru(III) versus Ru(II) oxidation states.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Likely contains synthesized experimental data from pharmacological evaluation.

Freshness

Last updated 2026-04-11 14:04:34; freshness should be verified.