FOLH1 Ligands with pIC50 Values and Molecular Properties

420 FOLH1 ligands with their corresponding pIC50 values, calculated molecular descriptors, structural and physicochemical properties. The dataset was authored by Rui Zhang and last updated on 2026-05-22. It is available as a 2.3 MB CSV file under a CC-BY-4.0 license.

Use Cases

• Train quantitative structure-activity relationship (QSAR) models based on the provided pIC50 values and molecular descriptors.
• Screen for potential FOLH1 inhibitors based on the structural and physicochemical property profiles.
• Analyze correlations between specific molecular descriptors and biological activity for the FOLH1 target.

Strengths

• Contains 420 specifically characterized FOLH1 ligands, providing a focused chemical space.
• Includes pIC50 values, enabling direct modeling of biological activity.
• Provides calculated molecular descriptors and physicochemical properties, reducing preprocessing effort.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Likely compiled from literature or computational screening for the FOLH1 target.

Time Range

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Freshness

Last updated 2026-05-22 17:42:51; freshness should be verified.

Geography

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