Mechanical and Osteogenic Properties of 3D-Printed PCL and β-TCP Bone Scaffold Lattices

Seven scaffold systems, including 3D-printed PCL and commercial β-TCP lattices, were mechanically tested and cultured with MG63 cells for 7 days. The dataset, authored by Shweta Thapa and shared on figshare in April 2026, compares grid, honeycomb, and gyroid architectures. Results link scaffold architecture and material to apparent Young's modulus, structural stiffness, and early cell proliferation and morphology.

Use Cases

• Compare the mechanical performance of different scaffold architectures based on apparent Young's modulus and structural stiffness data.
• Model the relationship between nanoscale topography and early osteogenic cell behavior based on proliferation and morphology assays.
• Derive design rules for bone scaffolds that balance stiffness and energy absorption based on the viscoelastic behavior of printed PCL lattices.
• Investigate the effect of continuous curvature and microrough surfaces on 3D cell colonization using data from gyroid lattice scaffolds.

Strengths

• Data compares seven distinct scaffold systems, including PCL nanofibers and β-TCP lattices in grid, honeycomb, and gyroid architectures.
• Includes results from monotonic tension mechanical testing and 7-day in vitro cell culture assays.
• File size is 4.4 MB, indicating a focused and likely manageable dataset for analysis.

Limitations

• Row count and column-level documentation are unknown; field semantics must be inferred after download.
• The study is limited to 7-day in vitro responses and air-tested mechanics, not long-term performance or hydrated conditions.

Provenance

Source

figshare, author Shweta Thapa.

Collection Method

Scaffolds were fabricated by fused-filament 3D printing or Direct Electrospin Writing, then mechanically tested and cultured with cells.

Freshness

Last updated 2026-04-22 08:13:56; freshness should be verified.