Renal Epithelial Cell Stiffness and Fibrosis Experimental Data

This dataset supports a study on how scaffold stiffening within a pathophysiological range disrupts tight junctions and promotes fibrosis in renal epithelial cells via p38 MAPK signaling. The data is associated with research on Epithelial Mesenchymal Transition, Tight Junction, and Extracellular Matrix Stiffness. The dataset was last updated in February 2026.

Use Cases

• Analyze the relationship between Extracellular Matrix Stiffness and Tight Junction protein expression levels.
• Investigate p38 MAPK signaling pathway activation in response to scaffold stiffening within the pathophysiological range.
• Model the progression of Epithelial Mesenchymal Transition using experimental data on fibrosis markers.

Strengths

• Data is directly linked to a specific, peer-reviewed study on renal epithelial cell mechanobiology.
• Dataset is tagged with specific biological processes: Epithelial Mesenchymal Transition, Tight Junction, and Extracellular Matrix Stiffness.
• The dataset was updated in February 2026, indicating recent maintenance.

Limitations

• The dataset's structure, including column names, row count, and file formats, is unknown.
• Sample data is unavailable, preventing assessment of data granularity or completeness.
• The specific experimental methods and measurement techniques used to generate the data are not described.

Provenance

Source

ICPSR Harvested Dataverse

Collection Method

Experimental data supporting a specific biological study.

Freshness

Last updated on 2026-02-23.