Serotonin depletion amplifies migraine susceptibility through trigeminal ganglion neurons

Figshare data from a study investigating serotonin depletion's role in migraine susceptibility via trigeminal ganglion neuron sensitization. The dataset includes electrophysiological parameters, correlation analyses, and demographic data for neuron groups, published under a CC-BY-4.0 license. It was last updated on 2026-05-13.

Use Cases

• Analyze correlations between electrophysiological parameters based on the Pearson correlation matrices.
• Compare excitability and action potential parameters across control and serotonin-depleted groups.
• Investigate demographic differences in trigeminal ganglion neuron populations.
• Validate statistical models of neuronal sensitization using the provided raw correlation data.

Strengths

• Dataset includes statistical significance markers (p < 0.05, < 0.01, < 0.001) for all analyses.
• Data is presented with mean ± SEM and uses multiple statistical tests (Kruskal–Wallis, ANOVA).
• Raw data for correlation heatmaps is provided in supporting tables.
• Files are available in multiple formats including TIF, TIFF, PNG, and PDF.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

Author: สิริกร Vongseenin. Platform: figshare.

Collection Method

Data likely collected via patch-clamp recording technique on trigeminal ganglion neurons.

Freshness

Last updated 2026-05-13 03:48:31; freshness should be verified.