HIV Cohort Serum Calcium and Liver Injury Data from Southeast China

A longitudinal cohort study of 2,726 people living with HIV (PLWH) with 10,621 blood samples collected over a median 2.9-year follow-up. The research, authored by Fang Liu, investigates U-shaped relationships between serum calcium levels and liver dysfunction/injury incidence. Proteomic analysis identified proteins F5, GDI2, and LDHA associated with both serum calcium and liver function.

Use Cases

• Modeling the risk of liver dysfunction based on serum calcium thresholds mentioned in the description
• Analyzing longitudinal associations between calcium levels and liver injury outcomes using Cox regression
• Investigating proteomic pathways linking calcium homeostasis to liver function via coagulation and glycolysis
• Evaluating calcium intake strategies for PLWH based on the identified reference levels

Strengths

• Includes 2,726 patient records with repetitive measurements totaling 10,621 blood samples
• Provides longitudinal data with a median follow-up period of 2.9 years
• Combines clinical measurements with proteomic analysis identifying specific proteins (F5, GDI2, LDHA)

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment

Provenance

Source

figshare

Collection Method

Retrospective longitudinal cohort study incorporating repetitive measurements and proteomic analysis.

Freshness

Last updated 2026-05-25 16:40:13; freshness should be verified

Geography

Southeast China