Sesquiterpenoids from Chrysanthemum indicum Flowers and Their Anti-Lung Cancer Activity

A 2.3 MB PDF published by Yonghao You on figshare in May 2026. It describes the isolation and identification of eight sesquiterpenoid compounds from the flower of Chrysanthemum indicum L. The study reports the significant cytotoxicity of one compound against three lung cancer cell lines, with IC50 values ranging from 0.84 ± 0.47 to 1.39 ± 0.75 μM.

Use Cases

• Identifying novel sesquiterpenoid structures based on the described isolation from Chrysanthemum indicum L.
• Screening for cytotoxic agents against lung cancer cell lines based on the reported IC50 values for A549, H1299, and Calu-1 cells.
• Comparative analysis of known compounds like chrysanthemumin A and B against newly discovered ones like Chryejuindion A and B.

Strengths

• Specific IC50 values (0.84 ± 0.47 to 1.39 ± 0.75 μM) are provided for cytotoxicity against three distinct lung cancer cell lines.
• The dataset is published under a permissive CC-BY-4.0 license, allowing for broad reuse.
• The description explicitly names eight specific compounds, including two newly described ones.

Limitations

• The primary data is contained in a 2.3 MB PDF; column-level documentation and structured data are absent.
• Row count and data structure are unknown, which may limit suitability assessment for computational analysis.
• Data may reflect the specific experimental and source bias inherent to a single research study on figshare.

Provenance

Source

figshare

Collection Method

Likely contains experimental data from the chemical separation and biological testing of compounds isolated from Chrysanthemum indicum L. flowers.

Freshness

Last updated 2026-05-04 10:20:03; freshness should be verified.