Simultaneous Induction of Ferroptosis and Immunogenic Cell Death by TrxR-Targeted Pt(IV) P

A dataset from a study on triple-negative breast cancer treatment, published on figshare. The data likely contains results from experiments with Pt(IV) prodrugs targeting thioredoxin reductase and DNA. The dataset was authored by Guimei Li and last updated on April 17, 2026.

Use Cases

• Analyzing drug efficacy against cisplatin-sensitive and -resistant cancer cells based on the described activity.
• Modeling the relationship between thioredoxin reductase inhibition and ferroptosis induction based on described pathways.
• Investigating the link between reactive oxygen species accumulation and endoplasmic reticulum stress based on the described mechanism.

Strengths

• Dataset is published under a CC-BY-NC-4.0 license, allowing non-commercial reuse with attribution.
• The description provides a detailed scientific context for the likely experimental results.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 1.2 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Likely contains experimental results from synthesized Pt(IV) prodrugs tested in vitro and in vivo.

Time Range

The study's temporal coverage is not specified.

Freshness

Last updated 2026-04-17 06:45:17; freshness should be verified.

Geography

The geographic scope of the research is not specified.