Single-cell DNA Sequencing Data from Meningioma Patients

142.2 MB of processed H5 files derived from single-nucleus DNA sequencing using the Mission Bio Tapestri platform. The data comprises single-nucleus-level read profiles, genotypes, and variant profiles from nuclei isolated from the meningeal dura of meningioma patients. It was authored by Young-soo Chung and last updated on 2026-05-23.

Use Cases

• Identify somatic mutations based on single-nucleus-level variant profiles
• Analyze clonal heterogeneity in meningioma based on single-nucleus genotypes
• Perform downstream genomic analysis using the recommended 'mosaic' pipeline

Strengths

• Data is provided in a processed H5 format ready for analysis, sized at 142.2 MB.
• The dataset focuses on a specific cancer type (meningioma) and tissue source (meningeal dura).

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

Young-soo Chung via figshare

Collection Method

Single-nucleus DNA sequencing using the Mission Bio Tapestri platform on nuclei isolated from patient tissue.

Freshness

Last updated 2026-05-23 13:15:13; freshness should be verified.