Single-Cell Imaging of Mitochondrial Metabolism in C2C12 Murine Skeletal Muscle Cells

Rozhin Penjweini's dataset from figshare, last updated 2026-05-29, provides single-cell imaging data on mitochondrial metabolism and remodeling during myogenic differentiation. The 882.7 MB collection includes fluorescence and redox imaging data to study intracellular oxygenation, ATP production, and mitochondrial dynamics. It offers a single-cell perspective on metabolic shifts and spatial organization in a murine skeletal muscle cell model.

Use Cases

• Analyzing metabolic heterogeneity during cell differentiation based on single-cell redox imaging data
• Studying the relationship between mitochondrial morphology and mobility based on morphological analyses mentioned in the description
• Investigating shifts in intracellular oxygenation and ATP production based on fluorescence imaging data
• Modeling the spatial organization of mitochondria relative to microtubules based on imaging approaches

Strengths

• Dataset size is 882.7 MB, indicating substantial raw data volume.
• Includes multiple complementary imaging approaches as described: fluorescence imaging, redox imaging, and morphological analyses.
• Data is hosted on figshare with a public domain (us-pd) license, facilitating reuse.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Various imaging approaches including fluorescence and redox imaging at the single-cell level, as described.

Freshness

Last updated 2026-05-29 17:54:18; freshness should be verified.