SIRT5-PRDX6 Axis Research Paper on Sepsis-Associated Acute Kidney Injury

A 439.1 KB research paper authored by Wenlong Lin, uploaded to figshare on April 10, 2026. The paper investigates the role of the SIRT5-PRDX6 axis in sepsis-associated acute kidney injury, using in vivo and in vitro models, proteomics analysis, and molecular assays.

Use Cases

• Analyze molecular pathways of ferroptosis based on described assays for HMOX1, GPX4, ACSL4, and Fe²⁺
• Study protein-protein interactions based on the described SIRT5-PRDX6 axis and desuccinylation sites
• Validate therapeutic targets for sepsis-associated acute kidney injury based on the described SIRT5 knockdown/overexpression experiments

Strengths

• The dataset is a research paper with a detailed experimental methodology described in the summary
• The dataset is openly licensed under CC-BY-4.0

Limitations

• The dataset is a 439.1 KB PDF/DOCX file, indicating a limited scope of raw data
• Row count and column-level documentation are absent; field semantics must be inferred after download

Provenance

Source

figshare

Collection Method

Likely contains experimental data from in vivo and in vitro sepsis models, proteomics analysis, and molecular assays.

Freshness

Last updated 2026-04-10 09:44:42